publications

selected publications  |  books  |  media

selected publications

2023

CAF variants control the tumor-immune microenvironment and predict skin cancer malignancy Forsthuber A, Korosec A, Jacob T, Aschenbrenner B, Annusver K, Frech S, Purkhauser K, Krajic N, Lipp K, Werner F, Nguyen V, Griss J, Bauer W, Soler Cardona A, Weber B, Weninger W, Gesslbauer B, Staud C, Nedomansky J, Radtke C, Wagner SN, Petzelbauer P, Kasper M, Lichtenberger BM. doi: https://doi.org/10.1101/2023.05.03.539213.

A Roadmap for a Consensus Human Skin Cell Atlas and Single-Cell Data Standardization. Almet AA, Yuan H, Annusver K, Ramos R, Liu Y, Wiedemann J, Sorkin DH, Landén NX, Sonkoly E, Haniffa M, Nie Q, Lichtenberger BM, Luecken MD, Andersen B, Tsoi LC, Watt FM, Gudjonsson JE, Plikus MV, Kasper M. J Invest Dermatol. 2023 Sep;143(9):1667-1677. doi: 10.1016/j.jid.2023.03.1679.

Molecular and spatial landmarks of early mouse skin development. Jacob T, Annusver K, Czarnewski P, Dalessandri T, Kalk C, Levra Levron C, Campamà Sanz N, Kastriti ME, Mikkola ML, Rendl M, Lichtenberger BM, Donati G, Björklund ÅK, Kasper M. Dev Cell. 2023 Aug 13:S1534-5807(23)00362-3. doi: 10.1016/j.devcel.2023.07.015.

Myofibroblast stroma differentiation in infiltrative basal cell carcinoma is accompanied by regulatory T-cells. Ressler JM, Zila N, Korosec A, Yu J, Silmbrod R, Bachmayr V, Tittes J, Strobl J, Lichtenberger BM, Hoeller C, Petzelbauer P. J Cutan Pathol. 2023 Jun;50(6):544-551. doi: 10.1111/cup.14381.

2022

Hedgehog Signaling in Papillary Fibroblasts Is Essential for Hair Follicle Regeneration during Wound Healing. Frech S, Forsthuber A, Korosec A, Lipp K, Kozumov V, Lichtenberger BM. J Invest Dermatol. 2022 Jun;142(6):1737-1748.e5. doi: 10.1016/j.jid.2021.11.026.

2021

Mus musculus papillomavirus 1 is a key driver of skin cancer development upon immunosuppression. Dorfer S, Strasser K, Schröckenfuchs G, Bonelli M, Bauer W, Kittler H, Cataisson C, Fischer MB, Lichtenberger BM and Handisurya A. Am J Transplant 2020 Oct, PMID: 33063442

Cellular heterogeneity and microenvironmental control of skin cancer.  Lichtenberger BM, Kasper M. J Intern Med. 2021 May;289(5):614-628. doi: 10.1111/joim.13177.

2020

Lipoatrophia semicircularis – a distinct entity?  Sigl J, Lázár M, Tittes J, Wendt J, Kancz S, Kiefer FW, Valencak J, Okamoto I, Lichtenberger BM, Handisurya A. Int J Dermatol. 2020 Nov;59(11):e385-e387. doi: 10.1111/ijd.15138.

Deciphering the functional heterogeneity of skin fibroblasts using single-cell RNA sequencing. Vorstandlechner V, Laggner M, Kalinina P, Haslik W, Radtke C, Shaw L, Lichtenberger BM, Tschachler E, Ankersmit HJ, Mildner M. FASEB J 2020 Mar, PMID: 31930613

Inhibition of p38/MK2 Signaling Prevents Vascular Invasion of Melanoma. Wenzina J, Holzner S, Puujalka E, Cheng PF, Forsthuber A, Neumüller K, Schossleitner K, Lichtenberger BM, Levesque MP, Petzelbauer P. JID 2020 Apr. PMID:  31622599

2019

Hair eruption initiates and commensal skin microbiota aggravate adverse events of anti-EGFR therapy.  Klufa J, Bauer T, Hanson B, Herbold C, Starkl P, Lichtenberger B, Srutkova D, Schulz D, Vujic I, Mohr T, Rappersberger K, Bodenmiller B, Kozakova H, Knapp S, Loy A, Sibilia M. Sci Transl Med. 2019 Dec 11;11(522):eaax2693. doi: 10.1126/scitranslmed.aax2693.

Preisträger der ÖGDV –  Fibroblastenidentität sowie Lokalisation in der Dermis bestimmen die Funktion von papillären und retikulären Fibroblasten in humaner Haut. Lichtenberger BM. J Dtsch Dermatol Ges. 2019 May, PMID: 31115983

Isolation of Papillary and Reticular Fibroblasts from Human Skin by Fluorescence-activated Cell Sorting Korosec A, Frech S, Lichtenberger BM. JoVE 2019 May, PMID: 31132050

EGFR Controls Hair Shaft Differentiation in a p53-Independent Manner.  Amberg N, Sotiropoulou PA, Heller G, Lichtenberger BM, Holcmann M, Camurdanoglu B, Baykuscheva-Gentscheva T, Blanpain C, Sibilia M. iScience. 2019 May 31;15:243-256. doi: 10.1016/j.isci.2019.04.018.

Fibroblastenidentität sowie Lokalisation in der Dermis bestimmen die Funktion. Korosec A, Frech S, Lichtenberger BM. Spectrum Dermatologie Jan 2019

2018

Lineage identity and location within the dermis determine the function of papillary and reticular fibroblasts in human skin. Korosec A, Frech S, Gesslbauer B, Vierhapper M, Radtke C, Petzelbauer P, Lichtenberger BM. J Invest Dermatol. 2018 Sep, PMID: 30179601

CXCL5 as Regulator of Neutrophil Function in Cutaneous Melanoma. Forsthuber A, Lipp K, Andersen L, Ebersberger S, Graña-Castro ‘, Ellmeier W, Petzelbauer P, Lichtenberger BM, Loewe R. J Invest Dermatol. 2019 Jan;139(1):186-194. doi: 10.1016/j.jid.2018.07.006.

An evolutionarily conserved ribosome-rescue pathway maintains epidermal homeostasis. Liakath-Ali K, Mills EW, Sequeira I, Lichtenberger BM, Pisco AO, Sipilä KH, Mishra A, Yoshikawa H, Wu CC, Ly T, Lamond AI, Adham IM, Green R, Watt FM. Nature. 2018 Apr;556(7701):376-380. doi: 10.1038/s41586-018-0032-3.

2017

Preisträger der ÖGDV Fibroblasten-Heterogenität in der Hautkrebsentstehung. Korosec A, Lichtenberger BM. J Dtsch Dermatol Ges. 2017 Aug 15, PMID: 28763603

Dermal Blimp1 acts downstream of epidermal TGFβ and Wnt/β-catenin to regulate hair follicle formation and growth. Telerman SB, Rognoni E, Sequeira I, Pisco AO, Lichtenberger BM, Culley O, Viswanathan P, Driskell RR, Watt FM. J Invest Dermatol. 2017 Jun 28, PMID: 28668474

A genome-wide screen identifies YAP/WBP2 interplay conferring growth advantage on human epidermal stem cells. Walko G, Woodhouse S, Pisco AO, Rognoni E, Liakath-Ali K, Lichtenberger BM, Mishra A, Telerman SB, Viswanathan P, Logtenberg M, Renz LM, Donati G, Quist SR, Watt FM. Nat Commun. 2017 Mar 23, PMID: 28332498

Epidermale ß-Catenin-Aktivierung reprogrammiert Fibroblasten und verändert die Dermis. Korosec A, Lichtenberger BM. Spectrum Dermatologie Jan 2017

Reply to Chi et al. Kaushal G, Rognoni E, Lichtenberger BM, Driskell RR, Kretzschmar K, Hoste E, Watt FM. J Invest Dermatol. 2017 Jan, PMID: 27638090

2016

Fibroblastenheterogenität und deren Auswirkung auf Hautkrebs. Lichtenberger BM. Jatros Hämatologie & Onkologie Oct 2016

β-Catenin Stabilization in Skin Fibroblasts Causes Fibrotic Lesions by Preventing Adipocyte Differentiation of the Reticular Dermis. Mastrogiannaki M, Lichtenberger BM, Reimer A, Collins CA, Driskell RR, Watt FM. J Invest Dermatol. 2016 Jun, PMID: 26902921

Epidermal β-catenin activation remodels the dermis via paracrine signalling to distinct fibroblast lineages. Lichtenberger BM, Mastrogiannaki M, Watt FM. Nat Commun. 2016 Feb 3, PMID: 26837596

2015

Fate of Prominin-1 Expressing Dermal Papilla Cells during Homeostasis, Wound Healing and Wnt Activation. Kaushal GS, Rognoni E, Lichtenberger BM, Driskell RR, Kretzschmar K, Hoste E, Watt FM. J Invest Dermatol. 2015 Dec, PMID: 26288357

2014

Epidermal Wnt/β-catenin signaling regulates adipocyte differentiation via secretion of adipogenic factors. Donati G, Proserpio V, Lichtenberger BM, Natsuga K, Sinclair R, Fujiwara H, Watt FM. Proc Natl Acad Sci U S A. 2014 Apr 15, PMID: 24706781

2013

Distinct fibroblast lineages determine dermal architecture in skin development and repair. Driskell RR, Lichtenberger BM, Hoste E, Kretzschmar K, Simons BD, Charalambous M, Ferron SR, Herault Y, Pavlovic G, Ferguson-Smith AC, Watt FM. Nature. 2013 Dec 12, PMID: 24336287

Divergent roles of HDAC1 and HDAC2 in the regulation of epidermal development and tumorigenesis. Winter M, Moser MA, Meunier D, Fischer C, Machat G, Mattes K, Lichtenberger BM, Brunmeir R, Weissmann S, Murko C, Humer C, Meischel T, Brosch G, Matthias P, Sibilia M, Seiser C. EMBO J. 2013 Dec 11, PMID: 24240174

Epidermal EGFR controls cutaneous host defense and prevents inflammation. Lichtenberger BM, Gerber PA, Holcmann M, Buhren BA, Amberg N, Smolle V, Schrumpf H, Boelke E, Ansari P, Mackenzie C, Wollenberg A, Kislat A, Fischer JW, Röck K, Harder J, Schröder JM, Homey B, Sibilia M. Sci Transl Med. 2013 Aug 21, PMID: 23966300

2010

Autocrine VEGF signaling synergizes with EGFR in tumor cells to promote epithelial cancer development.  Lichtenberger BM, Tan PK, Niederleithner H, Ferrara N, Petzelbauer P, Sibilia M. Cell. 2010 Jan 22, PMID: 20141840

2007

The epidermal growth factor receptor: from development to tumorigenesis. Sibilia M, Kroismayr R, Lichtenberger BM, Natarajan A, Hecking M, Holcmann M. Differentiation. 2007 Nov, PMID: 17999740

Regulation of dendritic cell differentiation and subset distribution by the zinc finger protein CTCF. Koesters C, Unger B, Bilic I, Schmidt U, Bluml S, Lichtenberger B, Schreiber M, Stockl J, Ellmeier W. Immunol Lett. 2007 Apr 15, PMID: 17368809

books

Elsevier Book “Advances in Stem Cells & their Niches Volume 3 – Epidermal Stem Cell Niche” (Aug 2019)
Editor: Mirna Perez-Moreno
Book chapter Six: Dermal Niche Signaling & Epidermal Stem Cells
Sophie Frech, Agnes Forsthuber, Ana Korosec and Beate M. Lichtenberger

Elsevier Book “Skin Tissue Models” (Nov 2017)
Editors: Alexandra Marques, Rui Reis, Rogério Pirraco, Mariana Cerqueria
Section 4  I  Book chapter: In vitro Models to study hair follicle generation – Growing hair in the dish
Ana Korosec and Beate M. Lichtenberger

media